This report provides a comprehensive review of avian pullorosis, a significant infectious disease affecting poultry populations worldwide. It delves into the causative agent, Salmonella Pullorum, and explores the pathogenesis, transmission routes, and resulting pathophysiology. Furthermore, the report examines the clinical signs and diagnostic methods employed in identifying the disease, along with various control and prevention strategies. Through a detailed analysis of these aspects, this document aims to enhance understanding of pullorosis and contribute to effective disease management in avian species, especially chickens.